LL-37
Cathelicidin LL-37
Source type: Human study. Sources checked .
What the cited research examined
A 148-patient trial tested topical LL-37 with compression therapy for venous leg ulcers.
The full study population showed no significant healing improvement. Exploratory subgroup findings require confirmation and do not support injectable use.
Reference facts
- Half-life
- Not established for general human use by the cited source.
- Human dose range
- Not provided. This reference does not recommend a human dose.
- Administration interval
- Not established by these sources. A half-life is not a dosing schedule.
- Storage
- Product-specific information required. These sources do not establish a storage specification.
Safety context
FDA notes immune concerns and unfavorable nonclinical safety findings.
Research results and substance listings are not product approvals. The FDA overview distinguishes current Category 2 entries from withdrawn nominations; withdrawal does not establish safety.
Sources and review method
- Phase IIb topical randomized trial
- FDA: bulk substances with potential safety risks (includes withdrawn nominations)
These are bounded summaries of the linked sources, not systematic reviews. An unknown field means that these sources do not establish a general-use value. It does not claim that no other literature exists.
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